Geometrical Frustration in Interleukin-33 Decouples the Dynamics of the Functional Element from the Folding Transition State Ensemble

Interleukin-33 (IL-33) is currently the focus of multiple investigations into targeting pernicious inflammatory disorders. This mediator of inflammation plays a prevalent role in chronic disorders such as asthma, rheumatoid arthritis, and progressive heart disease. In order to better understand the...

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Detalles Bibliográficos
Autores principales: Fisher, Kaitlin M., Haglund, Ellinor, Noel, Jeffrey K., Hailey, Kendra L., Onuchic, José N., Jennings, Patricia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667907/
https://www.ncbi.nlm.nih.gov/pubmed/26630011
http://dx.doi.org/10.1371/journal.pone.0144067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667907/
https://www.ncbi.nlm.nih.gov/pubmed/26630011
http://dx.doi.org/10.1371/journal.pone.0144067

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