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Human Metapneumovirus Is Capable of Entering Cells by Fusion with Endosomal Membranes

Human metapneumovirus (HMPV), a member of the Paramyxoviridae family, is a leading cause of lower respiratory illness. Although receptor binding is thought to initiate fusion at the plasma membrane for paramyxoviruses, the entry mechanism for HMPV is largely uncharacterized. Here we sought to determ...

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Detalles Bibliográficos
Autores principales: Cox, Reagan G., Mainou, Bernardo A., Johnson, Monika, Hastings, Andrew K., Schuster, Jennifer E., Dermody, Terence S., Williams, John V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667933/
https://www.ncbi.nlm.nih.gov/pubmed/26629703
http://dx.doi.org/10.1371/journal.ppat.1005303