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SNP Regulation of microRNA Expression and Subsequent Colon Cancer Risk

INTRODUCTION: MicroRNAs (miRNAs) regulate messenger RNAs (mRNAs) and as such have been implicated in a variety of diseases, including cancer. MiRNAs regulate mRNAs through binding of the miRNA 5’ seed sequence (~7–8 nucleotides) to the mRNA 3’ UTRs; polymorphisms in these regions have the potential...

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Detalles Bibliográficos
Autores principales: Mullany, Lila E., Wolff, Roger K., Herrick, Jennifer S., Buas, Matthew F., Slattery, Martha L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667940/
https://www.ncbi.nlm.nih.gov/pubmed/26630397
http://dx.doi.org/10.1371/journal.pone.0143894