AutoDockFR: Advances in Protein-Ligand Docking with Explicitly Specified Binding Site Flexibility

Automated docking of drug-like molecules into receptors is an essential tool in structure-based drug design. While modeling receptor flexibility is important for correctly predicting ligand binding, it still remains challenging. This work focuses on an approach in which receptor flexibility is model...

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Detalles Bibliográficos
Autores principales: Ravindranath, Pradeep Anand, Forli, Stefano, Goodsell, David S., Olson, Arthur J., Sanner, Michel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667975/
https://www.ncbi.nlm.nih.gov/pubmed/26629955
http://dx.doi.org/10.1371/journal.pcbi.1004586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667975/
https://www.ncbi.nlm.nih.gov/pubmed/26629955
http://dx.doi.org/10.1371/journal.pcbi.1004586

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