Lysosomal Enzyme Glucocerebrosidase Protects against Aβ(1-42) Oligomer-Induced Neurotoxicity

Glucocerebrosidase (GCase) functions as a lysosomal enzyme and its mutations are known to be related to many neurodegenerative diseases, including Gaucher’s disease (GD), Parkinson’s disease (PD), and Dementia with Lewy Bodies (DLB). However, there is little information about the role of GCase in th...

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Detalles Bibliográficos
Autores principales: Choi, Seulah, Kim, Donghoon, Kam, Tae-In, Yun, Seungpil, Kim, Sangjune, Park, Hyejin, Hwang, Heehong, Pletnikova, Olga, Troncoso, Juan C., Dawson, Valina L., Dawson, Ted M., Ko, Han Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668030/
https://www.ncbi.nlm.nih.gov/pubmed/26629917
http://dx.doi.org/10.1371/journal.pone.0143854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668030/
https://www.ncbi.nlm.nih.gov/pubmed/26629917
http://dx.doi.org/10.1371/journal.pone.0143854

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