T-Tau and P-Tau in Brain and Blood from Natural and Experimental Prion Diseases

Synaptic abnormalities are prominent in prion disease pathogenesis and are responsible for functional deficits. The microtubule associated protein, Tau, binds to and stabilizes microtubules in axons ensuring axonal transport of synaptic components. Tau phosphorylation reduces its affinity for microt...

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Detalles Bibliográficos
Autores principales: Rubenstein, Richard, Chang, Binggong, Petersen, Robert, Chiu, Allen, Davies, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668063/
https://www.ncbi.nlm.nih.gov/pubmed/26630676
http://dx.doi.org/10.1371/journal.pone.0143103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668063/
https://www.ncbi.nlm.nih.gov/pubmed/26630676
http://dx.doi.org/10.1371/journal.pone.0143103

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