Cargando…

T-Tau and P-Tau in Brain and Blood from Natural and Experimental Prion Diseases

Synaptic abnormalities are prominent in prion disease pathogenesis and are responsible for functional deficits. The microtubule associated protein, Tau, binds to and stabilizes microtubules in axons ensuring axonal transport of synaptic components. Tau phosphorylation reduces its affinity for microt...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rubenstein, Richard, Chang, Binggong, Petersen, Robert, Chiu, Allen, Davies, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668063/ https://www.ncbi.nlm.nih.gov/pubmed/26630676 http://dx.doi.org/10.1371/journal.pone.0143103

Ejemplares similares

Tau phosphorylation induced by severe closed head traumatic brain injury is linked to the cellular prion protein
por: Rubenstein, Richard, et al.
Publicado: (2017)

Novel Mouse Tauopathy Model for Repetitive Mild Traumatic Brain Injury: Evaluation of Long-Term Effects on Cognition and Biomarker Levels After Therapeutic Inhibition of Tau Phosphorylation
por: Rubenstein, Richard, et al.
Publicado: (2019)

Influence of Mabs on PrP(Sc) Formation Using In Vitro and Cell-Free Systems
por: Chang, Binggong, et al.
Publicado: (2012)

Tau, prions and Aβ: the triad of neurodegeneration
por: Reiniger, Lilla, et al.
Publicado: (2010)

Re-Assessment of PrP(Sc) Distribution in Sporadic and Variant CJD
por: Rubenstein, Richard, et al.
Publicado: (2013)

Alzheimer’s disease brain contains tau fractions with differential prion-like activities
por: Li, Longfei, et al.
Publicado: (2021)

Amyloid- and tau-PET imaging in a familial prion kindred
por: Jones, David T., et al.
Publicado: (2018)

Tau Lysine Pseudomethylation Regulates Microtubule Binding and Enhances Prion-like Tau Aggregation
por: Xia, Yuxing, et al.
Publicado: (2023)

Structure of Tau filaments in Prion protein amyloidoses
por: Hallinan, Grace I., et al.
Publicado: (2021)

No full admission for tau to the exclusive prion club yet
por: Polanco, Juan Carlos, et al.
Publicado: (2015)

The prion-like transmission of tau oligomers via exosomes
por: Jackson, Noel A., et al.
Publicado: (2022)

Targeting Prion-like Cis Phosphorylated Tau Pathology in Neurodegenerative Diseases
por: Albayram, Onder, et al.
Publicado: (2018)

FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments
por: Kaniyappan, Senthilvelrajan, et al.
Publicado: (2020)

The Tau polarization measurement at LEP and the nature of the $\tau W \nu_{\tau}$ coupling
por: Privitera, P
Publicado: (1992)

Plasma tau complements CSF tau and P-tau in the diagnosis of Alzheimer's disease
por: Fossati, Silvia, et al.
Publicado: (2019)

Cellular localization of p-tau217 in brain and its association with p-tau217 plasma levels
por: Wennström, Malin, et al.
Publicado: (2022)

Aβ and tau prions feature in the neuropathogenesis of Down syndrome
por: Condello, Carlo, et al.
Publicado: (2022)

Evolving prion-like tau conformers differentially alter postsynaptic proteins in neurons inoculated with distinct isolates of Alzheimer’s disease tau
por: Hromadkova, Lenka, et al.
Publicado: (2023)

CSF tau368/total-tau ratio reflects cognitive performance and neocortical tau better compared to p-tau181 and p-tau217 in cognitively impaired individuals
por: Simrén, Joel, et al.
Publicado: (2022)

Clinical and analytical comparison of six Simoa assays for plasma P-tau isoforms P-tau181, P-tau217, and P-tau231
por: Bayoumy, Sherif, et al.
Publicado: (2021)

The Prion 2018 round tables (II): Aβ, tau, α-synuclein… are they prions, prion-like proteins, or what?
por: Eraña, Hasier
Publicado: (2019)

Comparing tau status determined via plasma pTau181, pTau231 and [(18)F]MK6240 tau-PET
por: Tissot, Cécile, et al.
Publicado: (2022)

Detection of Alzheimer's disease amyloid beta 1‐42, p‐tau, and t‐tau assays
por: van Harten, Argonde C., et al.
Publicado: (2021)

Modeling Prion-Like Processing of Tau Protein in Alzheimer’s Disease for Pharmaceutical Development
por: Wischik, Claude M., et al.
Publicado: (2018)

Prion-Like Behavior and Tau-dependent Cytotoxicity of Pyroglutamylated β-Amyloid
por: Nussbaum, Justin M., et al.
Publicado: (2012)

What is the evidence that tau pathology spreads through prion-like propagation?
por: Mudher, Amrit, et al.
Publicado: (2017)

Variable tau accumulation in murine models with abnormal prion protein deposits
por: Piccardo, Pedro, et al.
Publicado: (2017)

Trans‐seeding of Alzheimer‐related tau protein by a yeast prion
por: Flach, Martin, et al.
Publicado: (2022)

Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo
por: Vasconcelos, Bruno, et al.
Publicado: (2016)

Tau accumulations in the brains of woodpeckers
por: Farah, George, et al.
Publicado: (2018)

Clinical performance and head-to-head comparison of CSF p-tau235 with p-tau181, p-tau217 and p-tau231 in two memory clinic cohorts
por: Lantero-Rodriguez, Juan, et al.
Publicado: (2023)

Measurement of \tau -> 3 \pi \nu _\tau branching ratio and P _\tau with the DELPHI detector
por: DELPHI Collaboration
Publicado: (2018)

Soluble P‐tau217 reflects amyloid and tau pathology and mediates the association of amyloid with tau
por: Mattsson‐Carlgren, Niklas, et al.
Publicado: (2021)

Experimental results on $\tau$ physics
por: Gómez-Cadenas, J J
Publicado: (1994)

Experimental introduction [ $\tau$ physics]
por: Stahl, A
Publicado: (2001)

Updated Measurement of the \tau Polarisation in \tau -> \tau(K)\nu_\tau
por: Moraes, D, et al.
Publicado: (1998)

Comparing the Clinical Utility and Diagnostic Performance of CSF P-Tau181, P-Tau217, and P-Tau231 Assays
por: Leuzy, Antoine, et al.
Publicado: (2021)

Search for the decays $B_s^0\to\tau^+\tau^-$ and $B^0\to\tau^+\tau^-$
por: Aaij, Roel, et al.
Publicado: (2017)

Guam ALS-PDC is a distinct double-prion disorder featuring both tau and Aβ prions
por: Condello, Carlo, et al.
Publicado: (2023)

The Sulfation Code of Tauopathies: Heparan Sulfate Proteoglycans in the Prion Like Spread of Tau Pathology
por: Mah, Dylan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qrsqqln7ftu3720846vf6kmi8m