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NDK Interacts with FtsZ and Converts GDP to GTP to Trigger FtsZ Polymerisation - A Novel Role for NDK

INTRODUCTION: Nucleoside diphosphate kinase (NDK), conserved across bacteria to humans, synthesises NTP from NDP and ATP. The eukaryotic homologue, the NDPK, uses ATP to phosphorylate the tubulin-bound GDP to GTP for tubulin polymerisation. The bacterial cytokinetic protein FtsZ, which is the tubuli...

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Detalles Bibliográficos
Autores principales: Mishra, Saurabh, Jakkala, Kishor, Srinivasan, Ramanujam, Arumugam, Muthu, Ranjeri, Raghavendra, Gupta, Prabuddha, Rajeswari, Haryadi, Ajitkumar, Parthasarathi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668074/
https://www.ncbi.nlm.nih.gov/pubmed/26630542
http://dx.doi.org/10.1371/journal.pone.0143677