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Primary Tumor-Secreted Lymphangiogenic Factors Induce Pre-Metastatic Lymphvascular Niche Formation at Sentinel Lymph Nodes in Oral Squamous Cell Carcinoma

OBJECTIVES: The objectives of this study were to evaluate the formation of lymphvascular niches in lymph nodes of patients with oral squamous cell carcinoma (OSCC), and investigate the roles of lymphangiogenic and angiogenic factors, such as vascular endothelial growth factor (VEGF)-A, VEGF-C, and V...

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Detalles Bibliográficos
Autores principales: Wakisaka, Naohiro, Hasegawa, Yasuhisa, Yoshimoto, Seiichi, Miura, Kouki, Shiotani, Akihiro, Yokoyama, Junkichi, Sugasawa, Masashi, Moriyama-Kita, Makiko, Endo, Kazuhira, Yoshizaki, Tomokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668078/
https://www.ncbi.nlm.nih.gov/pubmed/26630663
http://dx.doi.org/10.1371/journal.pone.0144056