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RNA-Based Vaccines in Cancer Immunotherapy

RNA vaccines traditionally consist of messenger RNA synthesized by in vitro transcription using a bacteriophage RNA polymerase and template DNA that encodes the antigen(s) of interest. Once administered and internalized by host cells, the mRNA transcripts are translated directly in the cytoplasm and...

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Detalles Bibliográficos
Autores principales: McNamara, Megan A., Nair, Smita K., Holl, Eda K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668311/
https://www.ncbi.nlm.nih.gov/pubmed/26665011
http://dx.doi.org/10.1155/2015/794528