Cargando…

Glycolipid Metabolism Disorder in the Liver of Obese Mice Is Improved by TUDCA via the Restoration of Defective Hepatic Autophagy

Objective. Tauroursodeoxycholic acid (TUDCA) has been considered an important regulator of energy metabolism in obesity. However, the mechanism underlying how TUDCA is involved in insulin resistance is not fully understood. We tested the effects of TUDCA on autophagic dysfunction in obese mice. Mate...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Qinyue, Shi, Qindong, Li, Huixia, Liu, Jiali, Wu, Shufang, Sun, Hongzhi, Zhou, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668323/
https://www.ncbi.nlm.nih.gov/pubmed/26681941
http://dx.doi.org/10.1155/2015/687938