MicroRNA-195 inhibits proliferation, invasion and metastasis in breast cancer cells by targeting FASN, HMGCR, ACACA and CYP27B1

De novo lipogenesis, a hallmark for cancers is required for cellular transformation. Further it is believed that resistance to apoptosis and epithelial-to-mesenchymal-transition(EMT) facilitates metastasis via over-expression of anti-apoptotic Bcl-2. Previously we demonstrated that hsa-miR-195 targe...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Richa, Yadav, Vikas, kumar, Sachin, Saini, Neeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668367/
https://www.ncbi.nlm.nih.gov/pubmed/26632252
http://dx.doi.org/10.1038/srep17454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668367/
https://www.ncbi.nlm.nih.gov/pubmed/26632252
http://dx.doi.org/10.1038/srep17454

Ejemplares similares