Acetaminophen cytotoxicity is ameliorated in a human liver organotypic co-culture model

Organotypic liver culture models for hepatotoxicity studies that mimic in vivo hepatic functionality could help facilitate improved strategies for early safety risk assessment during drug development. Interspecies differences in drug sensitivity and mechanistic profiles, low predictive capacity, and...

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Detalles Bibliográficos
Autores principales: Nelson, Leonard J., Navarro, Maria, Treskes, Philipp, Samuel, Kay, Tura-Ceide, Olga, Morley, Steven D., Hayes, Peter C., Plevris, John N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668374/
https://www.ncbi.nlm.nih.gov/pubmed/26632255
http://dx.doi.org/10.1038/srep17455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668374/
https://www.ncbi.nlm.nih.gov/pubmed/26632255
http://dx.doi.org/10.1038/srep17455

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