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Targeted exosome-mediated delivery of opioid receptor Mu siRNA for the treatment of morphine relapse

Cell-derived exosomes have been demonstrated to be efficient carriers of small RNAs to neighbouring or distant cells, highlighting the preponderance of exosomes as carriers for gene therapy over other artificial delivery tools. In the present study, we employed modified exosomes expressing the neuro...

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Detalles Bibliográficos
Autores principales: Liu, Yuchen, Li, Dameng, Liu, Zhengya, Zhou, Yu, Chu, Danping, Li, Xihan, Jiang, Xiaohong, Hou, Dongxia, Chen, Xi, Chen, Yuda, Yang, Zhanzhao, Jin, Ling, Jiang, Waner, Tian, Chenfei, Zhou, Geyu, Zen, Ke, Zhang, Junfeng, Zhang, Yujing, Li, Jing, Zhang, Chen-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668387/
https://www.ncbi.nlm.nih.gov/pubmed/26633001
http://dx.doi.org/10.1038/srep17543