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Mouse Crumbs3 sustains epithelial tissue morphogenesis in vivo

The human apical protein CRB3 (Crb3 in mouse) organizes epithelial cell polarity. Loss of CRB3 expression increases the tumorogenic potential of cultured epithelial cells and favors metastasis formation in nude mice. These data emphasize the need of in vivo models to study CRB3 functions. Here, we r...

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Detalles Bibliográficos
Autores principales: Charrier, Lucie E., Loie, Elise, Laprise, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668553/
https://www.ncbi.nlm.nih.gov/pubmed/26631503
http://dx.doi.org/10.1038/srep17699