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A small molecule inhibitor for ATPase activity of Hsp70 and Hsc70 enhances the immune response to protein antigens

The ATPase activities of Hsp70 and Hsc70 are known to be responsible for regulation of various biological processes. However, little is known about the roles of Hsp70 and Hsc70 in modulation of immune responses to antigens. In the present study, we investigated the effect of apoptozole (Az), a small...

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Detalles Bibliográficos
Autores principales: Baek, Kyung-Hwa, Zhang, Haiying, Lee, Bo Ryeong, Kwon, Young-Guen, Ha, Sang-Jun, Shin, Injae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668564/
https://www.ncbi.nlm.nih.gov/pubmed/26631605
http://dx.doi.org/10.1038/srep17642