TLR-3 stimulation improves anti-tumor immunity elicited by dendritic cell exosome-based vaccines in a murine model of melanoma

Dendritic cell (DC)-derived exosomes (Dexo) contain the machinery necessary to activate potent antigen-specific immune responses. As promising cell-free immunogens, Dexo have been tested in previous clinical trials for cancer vaccine immunotherapy, yet resulted in limited therapeutic benefit. Here,...

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Detalles Bibliográficos
Autores principales: Damo, Martina, Wilson, David S., Simeoni, Eleonora, Hubbell, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668567/
https://www.ncbi.nlm.nih.gov/pubmed/26631690
http://dx.doi.org/10.1038/srep17622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668567/
https://www.ncbi.nlm.nih.gov/pubmed/26631690
http://dx.doi.org/10.1038/srep17622

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