IL-10Rα expression is post-transcriptionally regulated by miR-15a, miR-185, and miR-211 in melanoma

BACKGROUND: IL-10 is an immunoregulatory cytokine that increases during malignant diseases. The purpose of this study was to: i) determine the mRNA amounts of IL-10, IL-10Rα, and IL-10Rβ in cutaneous and uveal melanoma cells and specimens; ii) evaluate their post-transcriptional regulation by miRNAs...

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Detalles Bibliográficos
Autores principales: Venza, Isabella, Visalli, Maria, Beninati, Concetta, Benfatto, Salvatore, Teti, Diana, Venza, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668633/
https://www.ncbi.nlm.nih.gov/pubmed/26631117
http://dx.doi.org/10.1186/s12920-015-0156-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668633/
https://www.ncbi.nlm.nih.gov/pubmed/26631117
http://dx.doi.org/10.1186/s12920-015-0156-3

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