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Dual Linkage of a Locus to Left Ventricular Mass and a Cardiac Gene Co-Expression Network Driven by a Chromosome Domain

We have previously reported Lvm1 as a quantitative trait locus (QTL) on chromosome 13 that links to cardiac left ventricular mass (LVM) in a panel of AxB/BxA mouse recombinant inbred strains (RIS). When performing a gene expression QTL (eQTL) analysis, we detected 33 cis-eQTLs that correlated with L...

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Detalles Bibliográficos
Autores principales: Scott-Boyer, Marie-Pier, Praktiknjo, Samantha D., Llamas, Bastien, Picard, Sylvie, Deschepper, Christian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668859/
https://www.ncbi.nlm.nih.gov/pubmed/26664861
http://dx.doi.org/10.3389/fcvm.2014.00011