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Self-defensive nano-assemblies from camptothecin-based antitumor drugs

Camptothecin (CPT)-based drugs always undergo the reversible, pH-dependent lactone ring-opening reaction, yielding the inactive but toxic carboxylate form. Self-assembly strategy provides an effective route for preserving their bio-stability. In this article, nano-sized self-assemblies from CPT-base...

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Detalles Bibliográficos
Autores principales: Qin, Si-Yong, Peng, Meng-Yun, Rong, Lei, Li, Bin, Wang, Shi-Bo, Cheng, Si-Xue, Zhuo, Ren-Xi, Zhang, Xian-Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669010/
https://www.ncbi.nlm.nih.gov/pubmed/26816639
http://dx.doi.org/10.1093/rb/rbv011