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Physiologic Stresses Reveal a Salmonella Persister State and TA Family Toxins Modulate Tolerance to These Stresses

Bacterial persister cells are considered a basis for chronic infections and relapse caused by bacterial pathogens. Persisters are phenotypic variants characterized by low metabolic activity and slow or no replication. This low metabolic state increases pathogen tolerance to antibiotics and host immu...

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Detalles Bibliográficos
Autores principales: Silva-Herzog, Eugenia, McDonald, Erin M., Crooks, Amy L., Detweiler, Corrella S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669091/
https://www.ncbi.nlm.nih.gov/pubmed/26633172
http://dx.doi.org/10.1371/journal.pone.0141343