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The Mammalian “Obesogen” Tributyltin Targets Hepatic Triglyceride Accumulation and the Transcriptional Regulation of Lipid Metabolism in the Liver and Brain of Zebrafish

Recent findings indicate that different Endocrine Disrupting Chemicals (EDCs) interfere with lipid metabolic pathways in mammals and promote fat accumulation, a previously unknown site of action for these compounds. The antifoulant and environmental pollutant tributyltin (TBT), which causes imposex...

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Detalles Bibliográficos
Autores principales: Lyssimachou, Angeliki, Santos, Joana G., André, Ana, Soares, Joana, Lima, Daniela, Guimarães, Laura, Almeida, C. Marisa R., Teixeira, Catarina, Castro, L. Filipe C., Santos, Miguel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669123/
https://www.ncbi.nlm.nih.gov/pubmed/26633012
http://dx.doi.org/10.1371/journal.pone.0143911