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Transient Cerebral Ischemia Promotes Brain Mitochondrial Dysfunction and Exacerbates Cognitive Impairments in Young 5xFAD Mice
Alzheimer's disease (AD) is heterogeneous and multifactorial neurological disorder; and the risk factors of AD still remain elusive. Recent studies have highlighted the role of vascular factors in promoting the progression of AD and have suggested that ischemic events increase the incidence of...
Autores principales: | Lu, Lin, Guo, Lan, Gauba, Esha, Tian, Jing, Wang, Lu, Tandon, Neha, Shankar, Malini, Beck, Simon J., Du, Yifeng, Du, Heng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669173/ https://www.ncbi.nlm.nih.gov/pubmed/26632816 http://dx.doi.org/10.1371/journal.pone.0144068 |
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