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Relationship between Initial Telomere Length, Initial Telomerase Activity, Age, and Replicative Capacity of Nucleus Pulposus Chondrocytes in Human Intervertebral Discs: What Is a Predictor of Replicative Potential?

There is evidence that telomere length (TL), telomerase activity (TA), and age are related to the replicative potential of human nucleus pulposus chondrocytes (NPCs). However, it has not yet been established if any of these factors can serve as predictors of the replicative potential of NPCs. To est...

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Detalles Bibliográficos
Autores principales: Lee, Jun-Seok, Jeong, Seo-Won, Cho, Sung-Wook, Juhn, Joon-Pyo, Kim, Ki-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669191/
https://www.ncbi.nlm.nih.gov/pubmed/26633809
http://dx.doi.org/10.1371/journal.pone.0144177