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Both IGF1R and INSR Knockdown Exert Antitumorigenic Effects in Prostate Cancer In Vitro and In Vivo

The IGF network with its main receptors IGF receptor 1 (IGF1R) and insulin receptor (INSR) is of major importance for cancer initiation and progression. To date, clinical studies targeting this network were disappointing and call for thorough analysis of the IGF network in cancer models. We highligh...

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Detalles Bibliográficos
Autores principales: Ofer, Philipp, Heidegger, Isabel, Eder, Iris E., Schöpf, Bernd, Neuwirt, Hannes, Geley, Stephan, Klocker, Helmut, Massoner, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669362/
https://www.ncbi.nlm.nih.gov/pubmed/26452103
http://dx.doi.org/10.1210/me.2015-1073