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Both IGF1R and INSR Knockdown Exert Antitumorigenic Effects in Prostate Cancer In Vitro and In Vivo
The IGF network with its main receptors IGF receptor 1 (IGF1R) and insulin receptor (INSR) is of major importance for cancer initiation and progression. To date, clinical studies targeting this network were disappointing and call for thorough analysis of the IGF network in cancer models. We highligh...
Autores principales: | Ofer, Philipp, Heidegger, Isabel, Eder, Iris E., Schöpf, Bernd, Neuwirt, Hannes, Geley, Stephan, Klocker, Helmut, Massoner, Petra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669362/ https://www.ncbi.nlm.nih.gov/pubmed/26452103 http://dx.doi.org/10.1210/me.2015-1073 |
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