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In-vitro and in-vivo evaluation of repaglinide loaded floating microspheres prepared from different viscosity grades of HPMC polymer

During the study repaglinide encapsulated floating microspheres were formulated and characterized for enhancing residence time of drug in git and thereby increasing its bioavailability. Floating microspheres of ethylcellulose (EC) and hydroxypropyl methyl cellulose (HPMC) (5 and 100 cps) were prepar...

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Detalles Bibliográficos
Autores principales: Sharma, Megha, Kohli, Seema, Dinda, Agnimitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669415/
https://www.ncbi.nlm.nih.gov/pubmed/26702263
http://dx.doi.org/10.1016/j.jsps.2015.02.013