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In vitro and in vivo targeting effect of folate decorated paclitaxel loaded PLA–TPGS nanoparticles

Paclitaxel is one of the most effective chemotherapeutic agents for treating various types of cancer. However, the clinical application of paclitaxel in cancer treatment is considerably limited due to its poor water solubility and low therapeutic index. Thus, it requires an urgent solution to improv...

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Detalles Bibliográficos
Autores principales: Thu, Ha Phuong, Nam, Nguyen Hoai, Quang, Bui Thuc, Son, Ho Anh, Toan, Nguyen Linh, Quang, Duong Tuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669427/
https://www.ncbi.nlm.nih.gov/pubmed/26702264
http://dx.doi.org/10.1016/j.jsps.2015.02.002