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The Comparative Studies of Binding Activity of Curcumin and Didemethylated Curcumin with Selenite: Hydrogen Bonding vs Acid-Base Interactions

In this report, the in vitro relative capabilities of curcumin (CCM) and didemethylated curcumin (DCCM) in preventing the selenite-induced crystallin aggregation were investigated by turbidity tests and isothermal titration calorimetry (ITC). DCCM showed better activity than CCM. The conformers of C...

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Detalles Bibliográficos
Autores principales: Liao, Jiahn-Haur, Wu, Tzu-Hua, Chen, Ming-Yi, Chen, Wei-Ting, Lu, Shou-Yun, Wang, Yi-Hsuan, Wang, Shao-Pin, Hsu, Yen-Min, Huang, Yi-Shiang, Huang, Zih-You, Lin, Yu-Ching, Chang, Ching-Ming, Huang, Fu-Yung, Wu, Shih-Hsiung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669449/
https://www.ncbi.nlm.nih.gov/pubmed/26635113
http://dx.doi.org/10.1038/srep17614