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Effects of histamine H1 receptor signaling on glucocorticoid receptor activity. Role of canonical and non-canonical pathways

Histamine H1 receptor (H1R) antagonists and glucocorticoid receptor (GR) agonists are used to treat inflammatory conditions such as allergic rhinitis, atopic dermatitis and asthma. Consistent with the high morbidity levels of such inflammatory conditions, these receptors are the targets of a vast nu...

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Detalles Bibliográficos
Autores principales: Zappia, Carlos Daniel, Granja-Galeano, Gina, Fernández, Natalia, Shayo, Carina, Davio, Carlos, Fitzsimons, Carlos P., Monczor, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669453/
https://www.ncbi.nlm.nih.gov/pubmed/26635083
http://dx.doi.org/10.1038/srep17476