Busulfan and cyclosphamide induce liver inflammation through NLRP3 activation in mice after hematopoietic stem cell transplantation

The aim of this study was to evaluate the role of NLRP3 inflammasome on BU/CY-induced liver inflammation in mice after HSCT. HSCT mice model was established through infusion of 5 × 10(6) bone marrow mononuclear cells after conditioned with BU/CY. On day 7, 14, 21 and 28 after HSCT, mice were sacrifi...

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Detalles Bibliográficos
Autores principales: Qiao, Jianlin, Huang, Yujin, Xia, Yuan, Chu, Peipei, Yao, Haina, Xu, Linyan, Qi, Kunming, Liu, Yun, Xu, Kailin, Zeng, Lingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669461/
https://www.ncbi.nlm.nih.gov/pubmed/26635145
http://dx.doi.org/10.1038/srep17828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669461/
https://www.ncbi.nlm.nih.gov/pubmed/26635145
http://dx.doi.org/10.1038/srep17828

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