Content and activity of human liver microsomal protein and prediction of individual hepatic clearance in vivo

The lack of information concerning individual variation in content and activity of human liver microsomal protein is one of the most important obstacles for designing personalized medicines. We demonstrated that the mean value of microsomal protein per gram of liver (MPPGL) was 39.46 mg/g in 128 hum...

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Detalles Bibliográficos
Autores principales: Zhang, Haifeng, Gao, Na, Tian, Xin, Liu, Tingting, Fang, Yan, Zhou, Jun, Wen, Qiang, Xu, Binbin, Qi, Bing, Gao, Jie, Li, Hongmeng, Jia, Linjing, Qiao, Hailing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669488/
https://www.ncbi.nlm.nih.gov/pubmed/26635233
http://dx.doi.org/10.1038/srep17671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669488/
https://www.ncbi.nlm.nih.gov/pubmed/26635233
http://dx.doi.org/10.1038/srep17671

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