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Cyclosporine A protects podocytes by regulating WAVE1 phosphorylation

Accumulating evidence suggests that podocytes are direct targets of many classic antiproteinuric drugs. The immunosuppressive drug cyclosporine A (CsA), which is a calcineurin inhibitor, is used to treat proteinuric kidney diseases. One novel mechanism by which CsA reduces proteinuria is by directly...

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Detalles Bibliográficos
Autores principales: Li, Xuejuan, Ding, Fangrui, Wang, Suxia, Li, Baihong, Ding, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669497/
https://www.ncbi.nlm.nih.gov/pubmed/26634693
http://dx.doi.org/10.1038/srep17694