The Malat1 long non-coding RNA is upregulated by signalling through the PERK axis of unfolded protein response during flavivirus infection

Flavivirus infection causes host cell death by initiation of an unfolded protein response (UPR). UPR is initiated following activation of three ER-membrane resident sensors, PERK, IRE1α and ATF6, which are otherwise kept inactive through association with the ER-chaperone GRP78. Activation precedes c...

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Detalles Bibliográficos
Autores principales: Bhattacharyya, Sankar, Vrati, Sudhanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669524/
https://www.ncbi.nlm.nih.gov/pubmed/26634309
http://dx.doi.org/10.1038/srep17794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669524/
https://www.ncbi.nlm.nih.gov/pubmed/26634309
http://dx.doi.org/10.1038/srep17794

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