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Transcriptional profiles of valvular interstitial cells cultured on tissue culture polystyrene, on 2D hydrogels, or within 3D hydrogels

Valvular interstitial cells (VICs) actively maintain and repair heart valve tissue; however, persistent activation of VICs to a myofibroblast phenotype can lead to aortic stenosis (Chen and Simmons, 2011) [1]. To better understand and quantify how microenvironmental cues influence VIC phenotype, we...

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Detalles Bibliográficos
Autores principales: Mabry, Kelly M., Payne, Samuel Z., Anseth, Kristi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669531/
https://www.ncbi.nlm.nih.gov/pubmed/26702427
http://dx.doi.org/10.1016/j.dib.2015.11.017