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Deep sequencing of HPV16 genomes: A new high-throughput tool for exploring the carcinogenicity and natural history of HPV16 infection

For unknown reasons, there is huge variability in risk conferred by different HPV types and, remarkably, strong differences even between closely related variant lineages within each type. HPV16 is a uniquely powerful carcinogenic type, causing approximately half of cervical cancer and most other HPV...

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Detalles Bibliográficos
Autores principales: Cullen, Michael, Boland, Joseph F., Schiffman, Mark, Zhang, Xijun, Wentzensen, Nicolas, Yang, Qi, Chen, Zigui, Yu, Kai, Mitchell, Jason, Roberson, David, Bass, Sara, Burdette, Laurie, Machado, Moara, Ravichandran, Sarangan, Luke, Brian, Machiela, Mitchell J., Andersen, Mark, Osentoski, Matt, Laptewicz, Michael, Wacholder, Sholom, Feldman, Ashlie, Raine-Bennett, Tina, Lorey, Thomas, Castle, Philip E., Yeager, Meredith, Burk, Robert D., Mirabello, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669577/
https://www.ncbi.nlm.nih.gov/pubmed/26645052
http://dx.doi.org/10.1016/j.pvr.2015.05.004