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M(3)-S: a genotype calling method incorporating information from samples with known genotypes

BACKGROUND: A key challenge in analyzing high throughput Single Nucleotide Polymorphism (SNP) arrays is the accurate inference of genotypes for SNPs with low minor allele frequencies. A number of calling algorithms have been developed to infer genotypes for common SNPs, but they are limited in their...

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Detalles Bibliográficos
Autores principales: Li, Gengxin, Zhao, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669649/
https://www.ncbi.nlm.nih.gov/pubmed/26634345
http://dx.doi.org/10.1186/s12859-015-0824-5