Cargando…
Identification of acetyltransferase genes (HAT1 and KAT8) regulating HBV replication by RNAi screening
BACKGROUND: The initiation of hepatitis B virus (HBV) replication involves the formation of covalently closed circular DNA (cccDNA) and its transcription into pregenomic RNA (pgRNA) in hepatocyte nuclei. The regulatory mechanism of HBV replication by acetyltransferase is thus far not well understood...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669656/ https://www.ncbi.nlm.nih.gov/pubmed/26640654 http://dx.doi.org/10.1186/s13578-015-0059-1 |