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Identification of acetyltransferase genes (HAT1 and KAT8) regulating HBV replication by RNAi screening

BACKGROUND: The initiation of hepatitis B virus (HBV) replication involves the formation of covalently closed circular DNA (cccDNA) and its transcription into pregenomic RNA (pgRNA) in hepatocyte nuclei. The regulatory mechanism of HBV replication by acetyltransferase is thus far not well understood...

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Detalles Bibliográficos
Autores principales:	Wang, Hui, Liu, KeHui, Fang, Bernard A. M., Wu, HaiQing, Li, FengDi, Xiang, XiaoGang, Tang, WeiLiang, Zhao, GangDe, Lin, LanYi, Bao, Shisan, Xie, Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669656/ https://www.ncbi.nlm.nih.gov/pubmed/26640654 http://dx.doi.org/10.1186/s13578-015-0059-1

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