Statistical considerations for stopping systemic lupus erythematosus clinical trials earlier

Group sequential designs are used to potentially shorten randomized clinical trials and thereby reduce subject burden, improve safety, and save time and resources. Clinical trials comparing treatments for systemic lupus erythematosus (SLE) might adopt such designs if the ordinal outcome scales for S...

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Detalles Bibliográficos
Autores principales: Lew, Robert A., Liang, Matthew H., Doros, Gheorghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669672/
https://www.ncbi.nlm.nih.gov/pubmed/26634344
http://dx.doi.org/10.1186/s13075-015-0874-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669672/
https://www.ncbi.nlm.nih.gov/pubmed/26634344
http://dx.doi.org/10.1186/s13075-015-0874-0

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