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Statistical considerations for stopping systemic lupus erythematosus clinical trials earlier
Group sequential designs are used to potentially shorten randomized clinical trials and thereby reduce subject burden, improve safety, and save time and resources. Clinical trials comparing treatments for systemic lupus erythematosus (SLE) might adopt such designs if the ordinal outcome scales for S...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669672/ https://www.ncbi.nlm.nih.gov/pubmed/26634344 http://dx.doi.org/10.1186/s13075-015-0874-0 |