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FAS-ligand regulates differential activation-induced cell death of human T-helper 1 and 17 cells in healthy donors and multiple sclerosis patients

Functionally distinct T-helper (Th) subsets orchestrate immune responses. Maintenance of homeostasis through the tight control of inflammatory Th cells is crucial to avoid autoimmune inflammation. Activation-Induced Cell Death (AICD) regulates homeostasis of T cells, and it has never been investigat...

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Detalles Bibliográficos
Autores principales: Cencioni, M T, Santini, S, Ruocco, G, Borsellino, G, De Bardi, M, Grasso, M G, Ruggieri, S, Gasperini, C, Centonze, D, Barilá, D, Battistini, L, Volpe, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669684/
https://www.ncbi.nlm.nih.gov/pubmed/25950471
http://dx.doi.org/10.1038/cddis.2015.100