Peptides derived from the dependence receptor ALK are proapoptotic for ALK-positive tumors

ALK is a receptor tyrosine kinase with an oncogenic role in various types of human malignancies. Despite constitutive activation of the kinase through gene alterations, such as chromosomal translocation, gene amplification or mutation, treatments with kinase inhibitors invariably lead to the develop...

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Detalles Bibliográficos
Autores principales: Aubry, A, Galiacy, S, Ceccato, L, Marchand, C, Tricoire, C, Lopez, F, Bremner, R, Racaud-Sultan, C, Monsarrat, B, Malecaze, F, Allouche, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669685/
https://www.ncbi.nlm.nih.gov/pubmed/25950466
http://dx.doi.org/10.1038/cddis.2015.102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669685/
https://www.ncbi.nlm.nih.gov/pubmed/25950466
http://dx.doi.org/10.1038/cddis.2015.102

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