Acetylation of HDAC1 and degradation of SIRT1 form a positive feedback loop to regulate p53 acetylation during heat-shock stress

The tumor suppressor p53 is an essential transcription factor that sensitively regulates cellular responses to various stresses. Acetylation, a critically important posttranslational modification of p53, is induced in response to cellular stresses. P53 acetylation level strongly correlates with prot...

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Detalles Bibliográficos
Autores principales: Yang, H, Yan, B, Liao, D, Huang, S, Qiu, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669686/
https://www.ncbi.nlm.nih.gov/pubmed/25950477
http://dx.doi.org/10.1038/cddis.2015.106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669686/
https://www.ncbi.nlm.nih.gov/pubmed/25950477
http://dx.doi.org/10.1038/cddis.2015.106

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