Impairment of enzymatic antioxidant defenses is associated with bilirubin-induced neuronal cell death in the cerebellum of Ugt1 KO mice

Severe hyperbilirubinemia is toxic during central nervous system development. Prolonged and uncontrolled high levels of unconjugated bilirubin lead to bilirubin-induced encephalopathy and eventually death by kernicterus. Despite extensive studies, the molecular and cellular mechanisms of bilirubin t...

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Detalles Bibliográficos
Autores principales: Bortolussi, G, Codarin, E, Antoniali, G, Vascotto, C, Vodret, S, Arena, S, Cesaratto, L, Scaloni, A, Tell, G, Muro, A F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669693/
https://www.ncbi.nlm.nih.gov/pubmed/25950469
http://dx.doi.org/10.1038/cddis.2015.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669693/
https://www.ncbi.nlm.nih.gov/pubmed/25950469
http://dx.doi.org/10.1038/cddis.2015.113

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