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Gankyrin drives malignant transformation of chronic liver damage-mediated fibrosis via the Rac1/JNK pathway
Hepatocarcinogenesis is a complex process involving chronic liver injury, inflammation, unregulated wound healing, subsequent fibrosis and carcinogenesis. To decipher the molecular mechanism underlying transition from chronic liver injury to dysplasia, we investigated the oncogenic role of gankyrin...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669699/ https://www.ncbi.nlm.nih.gov/pubmed/25950481 http://dx.doi.org/10.1038/cddis.2015.120 |