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Gankyrin drives malignant transformation of chronic liver damage-mediated fibrosis via the Rac1/JNK pathway

Hepatocarcinogenesis is a complex process involving chronic liver injury, inflammation, unregulated wound healing, subsequent fibrosis and carcinogenesis. To decipher the molecular mechanism underlying transition from chronic liver injury to dysplasia, we investigated the oncogenic role of gankyrin...

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Detalles Bibliográficos
Autores principales:	Zhao, X, Fu, J, Xu, A, Yu, L, Zhu, J, Dai, R, Su, B, Luo, T, Li, N, Qin, W, Wang, B, Jiang, J, Li, S, Chen, Y, Wang, H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669699/ https://www.ncbi.nlm.nih.gov/pubmed/25950481 http://dx.doi.org/10.1038/cddis.2015.120

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