Dual induction of apoptotic and autophagic cell death by targeting survivin in head neck squamous cell carcinoma

Survivin is ubiquitously expressed in patients with head neck squamous cell carcinoma (HNSCC) and is associated with poor survival and chemotherapy resistance. Sepantronium bromide (YM155) is a selective survivin suppressant that exhibits potent antitumor activities by inducing apoptosis and autopha...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, L, Zhang, W, Wang, Y-F, Liu, B, Zhang, W-F, Zhao, Y-F, Kulkarni, A B, Sun, Z-J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669714/
https://www.ncbi.nlm.nih.gov/pubmed/26018732
http://dx.doi.org/10.1038/cddis.2015.139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669714/
https://www.ncbi.nlm.nih.gov/pubmed/26018732
http://dx.doi.org/10.1038/cddis.2015.139

Ejemplares similares