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Dual induction of apoptotic and autophagic cell death by targeting survivin in head neck squamous cell carcinoma
Survivin is ubiquitously expressed in patients with head neck squamous cell carcinoma (HNSCC) and is associated with poor survival and chemotherapy resistance. Sepantronium bromide (YM155) is a selective survivin suppressant that exhibits potent antitumor activities by inducing apoptosis and autopha...
Autores principales: | Zhang, L, Zhang, W, Wang, Y-F, Liu, B, Zhang, W-F, Zhao, Y-F, Kulkarni, A B, Sun, Z-J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669714/ https://www.ncbi.nlm.nih.gov/pubmed/26018732 http://dx.doi.org/10.1038/cddis.2015.139 |
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