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Activation of NRG1-ERBB4 signaling potentiates mesenchymal stem cell-mediated myocardial repairs following myocardial infarction

Mesenchymal stem cell (MSC) transplantation has achieved only modest success in the treatment of ischemic heart disease owing to poor cell viability in the diseased microenvironment. Activation of the NRG1 (neuregulin1)-ERBB4 (v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4) signalin...

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Detalles Bibliográficos
Autores principales: Liang, X, Ding, Y, Zhang, Y, Chai, Y-H, He, J, Chiu, S-M, Gao, F, Tse, H-F, Lian, Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669719/
https://www.ncbi.nlm.nih.gov/pubmed/25996292
http://dx.doi.org/10.1038/cddis.2015.91